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There is currently a paucity of researchers conducting basic, clinical, and translational research on biodefense-related microbes and the methods to prevent and treat infections by these agents. Therefore, an important component of the New England Regional Center for Excellence for Biodefense and Emerging Diseases (NERCE) is the Career Development in Biodefense program, whose aim is to increase the pool of highly skilled investigators in all aspects of biodefense research. The goal of this portion of the Center is to train researchers and leaders of the highest caliber for research, clinical, product development, and administration of biodefense programs of the future.
Our career development program plan is to integrate the educational and training efforts in biodefense from both the basic science and clinical aspects. The objectives of this program are:
| Project | Principal Investigator |
| Studies on Ebola Virus Entry Into Cells | Kartik Chandran, Ph.D., Brigham and Women's Hospital |
| Analysis of Bacillus anthracis Genes Identified by IVIAT | Sean M. Rollins, Ph.D., Massachusetts General Hospital |
| Genomic Analysis of Poxvirus T Cell Epitopes | Stephen R. Walsh, M.D.C.M., Massachusetts General Hospital |
| Attenuated Listeria monocytogenes as a vector for viral antigens | Barbra McDonagh Blair, M.D., Massachusetts General Hospital |
| Identification of Cell-Surface Receptors of NIAID Priority Pathogens | Jens Holger Kuhn, Ph.D., M.D., M.S., New England Primate Research Center |
| Identification of RNA and protein modulators of Dengue virus translation | Glover W. Martin III, Ph.D., Massachusetts Institute of Technology |
| Distinct priming signals for T Cell effector / memory differentiation following smallpox vaccination | Luzheng Liu, M.D., Ph.D., Brigham and Women's Hospital |