| Project |
Principal Investigator |
|
Development of a Conjugate Vaccine for the Prevention of Tularemia |
Dennis Kasper, M.D., Brigham and Women's Hospital |
|
| Synthetic PNAG and multi-component vaccines against emerging pathogens |
Gerald Pier, Ph.D., Brigham and Women’s Hospital |
|
| Inhibitors of Type VI Secretion in NIAID Priority Pathogens |
Stephen Lory, Ph.D., Harvard Medical School |
|
| Tagged binding agents as improved anti-toxin therapeutics |
Charles Shoemaker, Ph.D., Tufts University |
|
| Cellular entry route for viral and bacterial pathogens |
Tomas Kirchhausen, Ph.D., Immune Disease Institute |
|
| COPI interactions mediate toxin entry: a common shared mechanism of translocation |
John R. Murphy, Ph.D., Boston Medical Center |
|
| Genomic approaches for discovering broad-spectrum antimicrobial agents |
Jon Clardy, Ph.D., Harvard Medical School |
|
| Identification and Characterization of Cellular Receptors for Enveloped Viruses |
Michael Farzan, Ph.D., Harvard Medical School; Hyeryun Choe, Ph.D., Children's Hospital |
|
| Treatments for Nipah Virus Infection |
Thomas Geisbert, Ph.D., Boston University |
|
| Novel antiviral targets in Ebola and Marburg virus polymerases |
Sean Whelan, Ph.D., Harvard Medical School |
|
| Discovery of small molecules to block fusion and entry of dengue and other enveloped viruses |
Stephen C. Harrison, Ph.D., Harvard Medical School |
|
| Innate immunity to hemorrhagic fever viruses |
Robert W. Finberg, M.D., University of Massachusetts |
|
| Inhibitors of Ebola Virus Infection |
James Cunningham, M.D., Brigham and Women’s Hospital |
Biomolecule Production